Lung cancer is the leading cause of cancer death in the United States, with 157,000 deaths annually,and in the world, with 1,375,000 deaths annually. The overall 5-year survival for lung cancer remains at 16%, which is signifi cantly lower than the mortality rate for other common cancers, including colon, breast,and prostate cancer. The discrepancy in the mortality rate of lung cancer compared with other cancers has several explanations. First, lung cancers are typically detected at an advanced stage. The anticipated implementation of population-based screening for lung cancer is expected to decrease mortality. Second, compared with the other common cancers that share adenocarcinoma as the histology, lung cancer is heterogenous histologically and biologically.
2014-04-15 编辑： faliuxue 来源：CHEST 2013; 143(5)(Suppl):e30S–e39S